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Studying In UK : link between COVID-19 vaccines and rare blood clots

A new, rapid nationwide study aiming to understand the vascular complications around blood clots after coronavirus vaccination is now underway.

New research has now begun following reports of a very rare condition involving blood clots and low platelet levels after COVID-19 vaccinations. The research is led by the British Heart Foundation (BHF) Data Science Centre – a partnership between UKRI-funded Health Data Research UK (HDR UK) and the BHF.

The rapid study will access healthcare records of all people in England. Firstly to identify who’s had a disease involving blood clots in the arteries or veins, and who’s been diagnosed with low platelet levels.

The study will then compare the risk of developing one of these conditions among people who have had a COVID-19 vaccine versus those who have not had a vaccine.

 

See further in Studying the link between blood clots and covid vaccines

Blood clot statistics 

COVID-19 vaccine

Overview: Although blood clots linked to the COVID vaccine remain extremely rare there appears to be a higher risk in people shortly after the first dose of the AstraZeneca (AZ) vaccine.

Risk rate: according to government guidance from June 2021, around 10 people develop this condition for every million of AZ vaccine doses given. That’s 0.001%.

Find out more at: COVID-19 vaccination and blood clotting (GOV.UK).

The combined oral contraceptive pill

Overview: The combined oral contraceptive pill contains artificial versions of female hormones oestrogen and progesterone. The oestrogen in the pill may, in rare cases, cause blood to clot more readily.

Risk rate: The estimated incidence of a blood clot with the combined oral contraceptive pill is about five per 10,000 women per year – a risk of one in 2,000, or 0.05%.

Find out more at: Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis (The BMJ).